Paper on Potential Novel Therapeutic for Shh-Driven Cancers Featured on Cover of Oncotarget
Thoracic Oncology Lab - - March 27, 2018
A team led by Bhairavi Tolani, Ph.D. and David M. Jablons, M.D. has developed and characterized a potential novel therapeutic for Sonic hedgehog (Shh)-driven cancers, including some lung cancers. Dr. Tolani is an assistant professor and member of the Thoracic Oncology Program, and principal investigator in the Tolani Laboratory. Dr. Jablons is director of the Thoracic Oncology Program and Thoracic Oncology Lab.
The researchers reported last October that full-length Shh protein present on the cell membrane identified cells with cancer stem cell (CSC) features implicated in NSCLC. To target [...]